Identification of embryonic RNA granules that act as sites of mRNA translation after changing their physical properties
Abstract
Fertilized eggs begin to translate mRNAs at appropriate times and placements to control development, but how the translation is regulated remains unclear. Here, we found that pou5f3 mRNA encoding a transcriptional factor essential for development formed granules in a dormant state in zebrafish oocytes. Although the number of pou5f3 granules remained constant, Pou5f3 protein accumulated…..
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Article Information:
Keisuke Sato, Moeko Sakai, Anna Ishii, Kaori Maehata, Yuki Takada, Kyota Yasuda, Tomoya Kotani,
Identification of embryonic RNA granules that act as sites of mRNA translation after changing their physical properties, iScience, Volume 25, Issue 6, 2022,
104344, ISSN 2589-0042,
DOI: 10.1016/j.isci.2022.104344
