ASHIKARI Yosuke
Specially Appointed Assistant Professor
Elucidating and manipulating organic reactive species
Department of Chemistry, Organic and Biological Chemistry
| Theme | Development of chemical reactions mediated by organic reactive species based on flow microsynthesis |
| Field | organic synthetic chemistry, organoelectro chemistry, flow chemistry |
| Keyword | reactive species, flow microsynthesis, organoelectro synthesis |
Introduction of Research
The research purpose is to develop chemical reactions that cannot be achieved with a conventional macro reactor, by using flow microreactors.
Representative Achievements
Flow grams-per-hour production enabled by hierarchical bimodal porous silica gel supported palladium column reactor having low pressure drop. Ashikari, Y.; Maekawa, K.; Takumi, M.; Tomiyasu, N.; Fujita, C.; Matsuyama, K.; Miyamoto, R.; Bai, H.; Nagaki, A. Catal. Today 2022, 388-389, 231-236.
Switchable Chemoselectivity of Reactive Intermediates Formation and Their Direct Use in a Flow Microreactor. Ashikari, Y.; Tamaki, T.; Kawaguchi, T.; Furusawa, M.; Yonekura, Y.; Ishikawa, S.; Takahashi, Y.; Aizawa, Y.; Nagaki, A. Chem. Eur. J. 2021, 27, 16107-16111.
A Synthetic Approach to Dimetallated Arenes Using Flow Microreactors and the Switchable Application to Chemoselective Cross-Coupling Reactions. Ashikari, Y.; Kawaguchi, T.; Mandai, K.; Aizawa, Y.; Nagaki, A. J. Am. Chem. Soc. 2020, 142, 17039-17047. (Cover Art)
A Novel Approach to Functionalization of Aryl Azides via Generation and Reactions of Organolithiums Bearing Masked Azides Using Flow Microreactors. Ichinari, D.; Ashikari, Y.; Mandai, K.; Aizawa, Y.; Yoshida, J.; Nagaki, A. Angew. Chem. Int. Ed. 2020, 59, 1567-1571.
Oxo-Thiolation of Cationically Polymerizable Alkenes Using Flow Microreactors. Ashikari, Y.; Saito, K.; Nokami, T.; Yoshida, J.; Nagaki, A. Chem. Eur. J. 2019, 25, 15239-15243. (Cover Art)
Related industries
chemistry, pharmaceuticals
| Academic degree | Ph.D |
| Self Introduction | I am researching everyday looking forward to new chemical discoveries and delicious foods. I am happy sharing excitement with collaborators through our research. |
| Academic background | 2008 B.S. Faculty of Engineering, Kyoto University 2010 M. Eng. Graduate School of Engineering, Kyoto University 2013 Ph.D. Graduate School of Engineering, Kyoto University 2013 Postdoctoral fellow, Graduate School of Engineering, Kyoto University 2014 Postdoctoral Fellow, Department of Chemistry, University of Washington 2017 Postdoctoral fellow, Department of Pharmacology, Keio University 2019 Postdoctoral fellow, Graduate School of Engineering, Kyoto University 2022 Postdoctoral fellow, Faculty of Science, Hokkaido University 2022 Specially Appointed Assistant Professor, Faculty of Science, Hokkaido University |
| Affiliated academic society | The chemical Society of Japan, The society of Synthetic Organic Chemistry, Japan |
| Room address | Science Building 7, 7-404 |
