Research News

First evidence of microtubules’ mechanosensitive behavior

Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, medicine, and biosensors.

See the Joint press release by Hokkaido University; the National Institutes of Natural Sciences; Research Center for Advanced Science and Technology (RCAST), The University of Tokyo; Yokohama City University; and Nagoya University.

From the left: Syeda Rubaiya Nasrin and Akira Kakugo, Hokkaido University; Christian Ganser, National Institutes of Natural Sciences; Takefumi Yamashita, RCAST, The University of Tokyo; Mitsunori Ikeguchi, Yokohama City University; Takayuki Uchihashi, Nagoya University; and Henry Hess, Columbia University (Photos: Syeda Rubaiya Nasrin, Akira Kakugo, Christian Ganser, Takefumi Yamashita, Mitsunori Ikeguchi, Takayuki Uchihashi, Henry Hess).

Original Article:
S. R. Nasrin, C. Ganser, S. Nishikawa, A. M. R. Kabir, K. Sada, T. Yamashita, M. Ikeguchi, T. Uchihashi, H. Hess, A. Kakugo, Deformation of microtubules regulates translocation dynamics of kinesin. Sci. Adv. 7, eabf2211 (2021).
DOI: 10.1126/sciadv.abf2211