Theoretical and Experimental Studies on the Near‐Infrared Photoreaction Mechanism of a Silicon Phthalocyanine Photoimmunotherapy Dye: Photoinduced Hydrolysis by Radical Anion Generation

KOBAYASHI Masato TAKETSUGU Tetsuya

Department of Chemistry

May. 26, 2020

Press release (in Japanese)

Abstract
Ligand release from IR700, a silicon phthalocyanine dye used in near-infrared (NIR) photoimmunotherapy, initiates cancer cell death after NIR absorption, although its photochemical mechanism has remained unclear. This theoretical study reveals that ……

Read more on ChemPlusChem

Article Information:
Kobayashi, M. et al. Theoretical and Experimental Studies on the Near‐Infrared Photoreaction Mechanism of a Silicon Phthalocyanine Photoimmunotherapy Dye: Photoinduced Hydrolysis by Radical Anion Generation. ChemPlusChem, May 25, 2020.
DOI: 10.1002/cplu.202000338