Research News

Cellular train track deformities shed light on neurological disease

A new technique allows researchers to test how the deformation of tiny train track-like cell proteins affects their function. The findings could help clarify the roles of deformed “microtubules” in traumatic brain injuries and in neurological diseases like Parkinson’s.

Joint press release by Hokkaido University and the National Institute of Information and Communications Technology (NICT)


From the left: Syeda Rubaiya Nasrin, Arif Md. Rashedul Kabir, Akira Kakugo and Kazuhiro Oiwa of the research team.


Original article:
Syeda Rubaiya Nasrin, Tanjina Afrin, et al., Regulation of biomolecular-motor-driven cargo transport by microtubules under mechanical stress. ACS Applied Bio Materials. March 5, 2020.
DOI: 10.1021/acsabm.9b01010

This study was supported by a Grant-in-Aid for Scientific Research on Innovative Areas (JP18H05423), a Grant-in-Aid for Young Scientists (B) (JP16K16383) from the Japan Society for the Promotion of Science (JSPS), and a research grant from Hirose International Scholarship Foundation (PK22181027).

Contacts / Further information:
See the press release (Hokkaido University website)