Researcher Information

MASUDA Yusuke

Assistant Professor

Department of Chemistry, Organic and Biological Chemistry

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FieldSynthetic chemistry, Organometallic chemistry, Photochemistry
KeywordPhotoreaction, Transition metal catalysis, Stereoselective reaction

Introduction of Research

Light, especially solar light, attracts much attention as a clean energy source. In the field of organic synthesis, light provides a reaction pathway different from that of a thermal reaction, and it offers a novel synthetic method to transform organic molecules. Focusing on the reactivity of radical intermediates generated by photoreaction, I am working on the use of common compounds such as carbon dioxide, water, sugars, and amino acids. I believe this approach would contribute to a sustainable society and the creation of new functional molecules. I also aim to discover unknown phenomena and properties of organic molecules through the development of reactions and contribute to the further development of chemistry.

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Photoinduced transformation of organic molecules

Representative Achievements

Photocatalytic 1,2-Phosphorus-Migrative [3+2] Cycloaddition of Tri(t-butyl)phosphine with Terminal Alkynes.
Y. Masuda, D. Ikeshita, K. Higashida, M. Yoshida, N. Ishida, M. Murakami, M. Sawamura, M.
J. Am. Chem. Soc. 2023, 145, 19060–19066.
Photoinduced Alcoholic α-C–H Bond Anti-Markovnikov Addition to Vinylphosphonium Bromides Followed by Wittig Olefination: Two-step Protocol for α-C–H Allylic Alkylation of Alcohols.
M. Yoshida, M. Sawamura, Y. Masuda
ChemCatChem 2022, 14, e202200744
Photoinduced Copper-Catalyzed Asymmetric Acylation of Allylic Phosphates with Acylsilanes
Y. Ueda, Y. Masuda, T. Iwai, K. Imaeda, H. Takeuchi, K. Ueno, M. Gao, J. Hasegawa, M. Sawamura
J. Am. Chem. Soc. 2022, 144, 2218-2224
Photo-induced Dearomatizing Three-component Coupling of Arylphosphines, Alkenes, and Water
Y. Masuda, H. Tsuda, M. Murakami
Angew. Chem. Int. Ed. 2021, 60, 3551-3555
C-1 Oxidation/C-2 Reduction Isomerization of Unprotected Aldoses Induced by Light/Ketone
Y. Masuda, H. Tsuda, M. Murakami
Angew. Chem., Int. Ed., 2020, 59, 2755-2759

Related industries

Chemical products, Pharmaceuticals, Functional materials
Academic degreePh.D.
Self Introduction

Let's enjoy chemistry!

Academic background2012 B.S.. Kyoto University
2014 M.S.. Graduate School of Engineering, Kyoto University
2017 Ph.D. Graduate School of Engineering, Kyoto University
2017 JSPS Research Fellow (SPD), The University of Tokyo
2017 Visiting Scientist, California Institute of Technology
2018 Assistant Professor, Kyoto University
2021 Assistant Professor, Hokkaido University
Affiliated academic societyThe Chemical Society of Japan, The Society of Synthetic Organic Chemistry, Japan
Room addressScience Building 6 6-608
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