Researcher Information

RYUZAKI Sou

Associate Professor

Single particle/molecule analysis by Plasmonics

Department of Chemistry, Inorganic and Analytical Chemistry

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Theme

Understanding and applications of nanophotonics for analytical chemistry

FieldAnalytical chemistry, Surface/interfacial Physics, Optical physics, Machine learning
KeywordPlasmonics, Nanobiodevices, Organic devices, 2D materials, Single particle/molecule analysis, First principle calculation

Introduction of Research

To understand nanophotonics generated around nanostrcutres and to apply nanophotonics to novel analytical technologies and biosensors. Specifically, we work on the plasmonic enhancement field obtained by the resonance of light with free electrons in nanostructures. Understandings the plasmonic properties of various materials such as metals and graphene from the viewpoint of electronic and optical properties enable us to control them, and finally to analyze single molecules and/or single nanoparticles by using the plasmonic enhancement field. For example, we are recently interested in plasmonic nanopore devices for DNA, RNA, and bio-nanoparticles.

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Schematic illustration of Nanopore device
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Graphene nanopore
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Multiphysics simulation
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Schematic illustration of plasmonic metal nanoparticles
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Chemically Induced Permittivity-change effect
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Original high-speed CCD detector

Representative Achievements

Effect of chemically induced permittivity changes on the plasmonic properties of metal nanoparticles,
N. Saito, S. Ryuzaki*, Y. Tsuji, Y. Noguchi, P. Wang, D. Tanaka, Y. Arima, K. Okamoto, K. Yoshizawa, and K. Tamada,
Commun. Mater. 2, 54 (2021).
Rapid discrimination of extracellular vesicles by shape distribution analysis,
S. Ryuzaki*, T. Yasui, M. Tsutsui, K. Yokota, Y. Komoto, P. Paisrisarn, N. Kaji, D. Ito, K. Tamada, T. Ochiya, M. Taniguchi, Y. Baba, and T. Kawai,
Anal. Chem. 93, 7037 (2021). (Cover Art).
Field effect control of translocation dynamic in surround-gate nanopores,
M. Tsutsui, S. Ryuzaki, K. Yokota, H. Yuhui, T. Washio, K. Tamada, and T. Kawai,
Commun. Mater. 2, 29 (2021). (Co-first author, Cover Art).
Rapid structural analysis of nanomaterials in aqueous solutions,
S. Ryuzaki, M. Tsutsui, Y. He, K. Yokota, A. Arima, T. Morikawa, M. Taniguchi, and T. Kawai,
Nanotechnology 28, 155501 (2017).
An influence of charge accumulation of photo-generated carriers in the vicinity of donor/acceptor interface on the open-circuit voltage of Zinc- porphyrin/C60 hetero-junction organic photovoltaic cells,
S. Ryuzaki and J. Onoe,
J. Phys. D: Appl. Phys., 44, 265102 (2011).

Related industries

Chemistry, Physics, Material physics, Medical device, Energy
Academic degreePh.D.
Academic background2005 B.A., Department of Physics, Tokyo University of Science
2010 M.S., Department of Nuclear Engineering, Tokyo Institute of Technology
2010 Ph.D., Department of Nuclear Engineering, Tokyo Institute of Technology
2010 Postdoc., Nano-Science Center, University of Copenhagen
2012 Assistant Professor, The Institute of Scientific and Industrial Research, Osaka University
2014 Assistant Professor, Institute for Materials Chemistry and Engineering, Kyushu University
2022 Associate Professor, Department of Chemistry Hokkaido University
Affiliated academic societyThe Japan Society of Applied Physics, The Japan Society for Analytical Chemistry, The Society of Nano Science and Tchnology, Japan MRS, American Chemical Society
ProjectJST CREST
Room addressScience Building 6, 7-02.

Department of Chemistry, Inorganic and Analytical Chemistry

RYUZAKI Sou

Associate Professor

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What is the research theme that you are currently focusing on?

Recently, I’ve been deeply involved in developing biosensors using our proprietary technology. Specifically, these sensors are designed to detect various diseases, primarily cancer, from bodily fluids in a simple and cost-effective manner. Furthermore, by measuring any types of bodily fluids with these sensors, we are also investigating unexplained phenomena related to the human body. Since this research is enable by our unique measurement technology, and often yields unexpected data, it one of the most exciting research themes.

Schematic illustration of the biosensor.
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Please tell us about yourself; things you are good at, your favorites, hobbies, and daily routines.

I had many opportunities to be exposed to music as a child, so I still love music. My favorite genre is progressive rock. Recently, I’ve been cherishing the time I spend with my son, especially taking him to and from daycare, which has become a daily routine I enjoy. I feel his growth every day.

My son strolling in the park.
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Please tell us your stories until you became a researcher.

When I was a student, I worked on organic solar cells that mimic photosynthesis. The more I studied, the more I realized how incredible photosynthesis is, and by the time I completed my PhD degree, my research interests had expanded to include biological fields. Since my specialization was in materials science and not biology, I was unsure what kind of researcher I wanted to become at the time. However, I eventually decided to focus on interdisciplinary research, leveraging my wide range of interests. The research I am currently working on involves various elements such as condensed matter physics, optics, analytical chemistry, molecular biology, and AI. While it can be challenging, the interdisciplinary nature of the work leads to unique outcomes, and I find it very rewarding as a researcher.

Dinner with my former colleagues from Denmark in Tokyo
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