Researcher Information


Assistant Professor

Dynamics of plant organelle

Department of Biological Sciences, Cell Structure and Function


Organelle dynamics for environmental adaptation in plants

FieldPlant physiology, Cell biology
KeywordEnvironmental response, Posttranscriptional modification, Organelle, Membrane traffic/vesicle transport, Live cell imaging

Introduction of Research

Within the eukaryotic cells, there are various structures surrounded by membranes called organelles. Organelles have their unique composition of proteins and lipids, and are responsible for their unique metabolic functions. Membrane traffic with membrane-bound vesicles that deliver cargoes to their destinations plays an important role in maintaining organelle homeostasis. Plants regulates the membrane traffic system and flexibly changes organelles in response to various environmental stresses. By using live cell imaging and biochemical analysis, we aim to elucidate the dynamics of organelles and membrane traffic systems in response to environmental changes, and to understand the flexible environmental adaptation strategies of plants. We are also interested in how organelles are maintained throughout the life of plants.

Plant Organelles
Endoplasmic reticulum (magenta) and Golgi stacks (green) in cotyledon epidermal cells of Arabidopsis thaliana
Endoplasmic reticulum subdomain for vesicle formation (green) transiently contact with Golgi stacks (magenta) which formed vescles are destined for

Representative Achievements

Dynamic Capture-and-Release of Endoplasmic Reticulum Exit Sites by Golgi Stacks in Arabidopsis (2020) Takagi J., Kimori Y., Shimada T., Hara-Nishimura I. iScience. 23(7):101265.
A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis (2019) Uemura T., Nakano R. T., Takagi J., Wang Y., Kramer K., Finkemeier I., Nakagami H., Tsuda K., Ueda T., Schulze-Lefert P., Nakano A. Plant Physiol. 179(2):519-532.
Plant Vacuoles (2018) Shimada T., Takagi J., Ichino T., Shirakawa M., Hara-Nishimura I. Annu. Rev. Plant Biol. 69:123-145.
MAIGO5 Functions in Protein Export from Golgi-Associated Endoplasmic Reticulum Exit Sites in Arabidopsis (2013) Takagi J., Renna L., Takahashi H., Koumoto Y., Tamura K., Stefano G., Fukao Y., Kondo M., Nishimura M., Shimada T., Brandizzi F., Hara-Nishimura I. Plant Cell. 25(11):4658-75.
MAG4/Atp115 is a Golgi-Localized Tethering Factor that Mediates Efficient Anterograde Transport in Arabidopsis (2010) Takahashi H., Tamura K., Takagi J., Koumoto Y., Hara-Nishimura I., Shimada T. Plant Cell Physiol. 51(10):1777-87.
Academic degreePh. D.
Academic background2014 Ph.D., Graduate School of Science, Kyoto University
2014 Postdoctoral Fellow, Graduate School of Science, Kyoto University
2015 JSPS Fellow (PD), Graduate School of Science, The University of Tokyo
2017 Specially Appointed Research Assistant Professor, Fuculty of Science and Engineering, Konan University
2020- Assistant Professor, Faculty of Science, Hokkaido University
Affiliated academic societyThe Japanese Society of Plant Physiologists
Room addressScience Building 5 5-710