Researcher Information


Assistant Professor

Designing the Movement of Supramolecules

Department of Chemistry, Organic and Biological Chemistry


Development of functional interlocked compounds

FieldSupramolecular chemistry, Photochemistry, Synthetic organic chemistry
KeywordHost-guest complexes, Cyclodextrins, Rotaxanes, Luminescent materials, Molecular machine

Introduction of Research

Mechanically interlocked molecules (MIMs) are molecules mechanically bonded through molecular entanglements that cannot be disassembled into their components without cleaving a covalent bond. During my doctoral studies, I worked on improving the performance of photofunctional materials. Recently, I have achieved to develop a novel molecular machine by precisely controlling the movement of MIMs. In the future, I would like to integrate such supramolecular chemistry with microflow technology, which enables precise control of the kinetics of supramolecular motion and paves the way to unprecedented molecular machines.

Improvement of fluorescence efficiency by [1]rotaxane structures

Representative Achievements

Miyagishi, H. V.; Masai, H.; Terao, J.
Linked Rotaxane Structure Restricts Local Molecular Motions in Solution to Enhance Fluorescence Properties of Tetraphenylethylene.
Chem. Eur. J. 2022, 28, e202103175. (Selected as Very Important Paper)
Miyagishi, H. V.; Masai, H.; Terao, J.
Suppression of Undesirable Isomerization and Intermolecular Reactions of Double Bonds by a Linked Rotaxane Structure.
Chem. Asian J. 2020, 15, 1890–1895.
Shimada, S.; Miyagishi, H. V.; Masai, H.; Masui, Y.; Terao, J.
Solvatofluorochromic Contrast with Supramolecular Stereoisomers Using Linked Rotaxane Structures to Investigate Local Solvation in Excited Donor-Bridge-Acceptor Systems.
Bull. Chem. Soc. Jpn. 2022, 95, 163–168.

Related industries

Self Introduction

Since I can remember, I have been moving further and further north, living in Kagoshima, Tokyo, and now Hokkaido. I have specialized in supramolecular chemistry and photochemistry, and I would like to explore new research areas by merging them with flow technology. My hobby is music, and I particularly enjoy the music in New Orleans. I mainly play the sousaphone in live performances.

Academic background2018 Bachelor degree, Department of Applied Chemistry, School of Advance Science and Engineering, Waseda University
2020 Master degree, Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo
2021 JSPS Research Fellowships for Young Scientists (DC2)
2023 Ph. D., Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo
2023- Assistant Professor, Faculty of Science Department of Chemistry, Hokkaido University
Affiliated academic societyThe Chemical Society of Japan, The Society of Physical Organic Chemistry, Association of Research for Host-Guest and Supramolecular Chemistry, The Society of Cyclodextrins
Room addressScience Building 7, 7-404