Flowmicro In-Line Analysis-Driven Design of Reactions mediated by Unstable Intermediates: Flash Monitoring Approach
Press release (in Japanese)
Abstract
The direct observation of reactive intermediates is an important issue for organic synthesis. However, intermediates with an extreme instability are hard to be monitored by common spectroscopic methods such as FTIR. We have developed synthetic method utilizing flow microreactors, which enables a generation and reactions of unstable intermediates. Herein we report that, based on our flowmicro techniques, we developed an in-line analysis method for reactive intermediates in increments of milliseconds. We demonstrated….
Read the original article on Chemistry: A European Journal
Article Information:
Yosuke Ashikari, Rikako Yoshioka, Yuya Yonekura, Kazuhiro Okamoto, Aiichiro Nagaki
Flowmicro In-Line Analysis-Driven Design of Reactions mediated by Unstable Intermediates: Flash Monitoring Approach. Chemistry: A European Journal, 12 March 2024
DOI:10.1002/chem.202303774
