Researcher Information

Yohei Shimizu

Lecturer

Development of novel catalyst

Department of Chemistry, Organic and Biological Chemistry

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Theme

Development of chemoselective reactions based on novel catalyst

FieldOrganometalic chemistry, Organic synthesis chemistry
KeywordChemoselective reaction, Boron catalyst, Photo catalyst, Copper catalyst
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Summary of my research

Representative Achievements

Chemo- and Enantioselective Pd/B Hybrid Catalysis for the Construction of Acyclic Quaternary Carbons: Migratory Allylation of O-Allyl Esters to α-C-Allyl Carboxylic Acids
Fujita, T.; Yamamoto, T.; Morita, Y.; Chen, H.; Shimizu, Y.*; Kanai, M.*
J. Am. Chem. Soc. 2018, 140, 5899-5903.
Chemoselective Boron-Catalyzed Nucleophilic Activation of Carboxylic Acids for Mannich-Type Reactions
Morita Y.; Yamamoto T.; Nagai H.; Shimizu Y.*; Kanai M.*
J. Am. Chem. Soc. 2015, 137, 7075-7078.
An Expeditious Synthesis of Sialic Acid Derivatives by Copper(I)-Catalyzed Stereodivergent Propargylation of Unprotected Aldoses
Wei, X.-F.; Shimizu, Y.*; Kanai, M.*
ACS Cent. Sci. 2016, 2, 21-26. (Cover picture)
Ligand-Enabled, Copper-Catalyzed Regio- and Stereoselective Synthesis of Trialkylsubstituted Alkenylboronates from Unactivated Internal Alkynes
Itoh, T.; Shimizu, Y.; Kanai, M.*
J. Am. Chem. Soc. 2016, 138, 7528-7531.
Copper(I)-Catalyzed Enantioselective Addition of Enynes to Ketones
Wei, X.-F.; Xie, X.-W.; Shimizu, Y.*; Kanai, M.*
J. Am Chem. Soc. 2017, 139, 4647-4650.
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Related industries

Pharmaceutical, Cosmetic, Fine chemistry
Academic degreePh.D.
Academic background2006.3 BS
Department of Pharmaceutical Sciences, The University of Tokyo
2008.3 Master
Graduate School of Pharmaceutical Sciences, The University of Tokyo
2011.3 Ph.D.
Graduate School of Pharmaceutical Sciences, The University of Tokyo
2011.4-2017.12 Assistant Professor
Graduate School of Pharmaceutical Sciences, The University of Tokyo
2012.7-2012.9 Visiting Scientist
Department of Chemistry, University of Cambridge
2018.1-present Lecturer
Department of Chemistry , Faculty of Science, Hokkaido University
Affiliated academic societyThe Chemical Society of Japan, The Pharmaceutical Society of Japan, The Society of Synthetic Organic Chemistry, Japan