Researcher Information

Fujimori Chika

Assistant Professor

Understanding Gonadal Differences from Genome Sequence

Department of Biological Sciences, Reproductive and Developmental Biology


Understanding evolutionary changes in the expression and function of genes involved in vertebrate gonadal function from genomics

FieldMolecular biology, Reproductive biology, Comparative endocrinology
KeywordHormone, Gonad, Ovary, Testis, Enhancer, Evolution

Introduction of Research

Gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), and luteinizing hormone (LH) are essential for vertebrate gonadal function, but their expression and function have been revealed to be different among vertebrate lineages. I am interested in experimentally comparing the genomes of various organisms to determine when and how their expression and function changed during evolution, and what genomic changes caused these changes.

Representative Achievements

Fujimori C, Umatani C, Chimura M, Ijiri S, Bando H, Hyodo S, Kanda S. In vitro and in vivo gene transfer in the cloudy catshark Scyliorhinus torazame. Dev Growth Differ. 2022
Ogiwara K, Fujimori C, Takahashi T. The PGE2/Ptger4b pathway regulates ovulation by inducing intracellular actin cytoskeleton rearrangement via the Rho/Rock pathway in the granulosa cells of periovulatory follicles in the teleost medaka. Mol Cell Endocrinol. 2023 Jan 15;560:111816.
Fujimori C, Ogiwara K, Hagiwara A, Takahashi T. New evidence for the involvement of prostaglandin receptor EP4b in ovulation of the medaka, Oryzias latipes. Mol Cell Endocrinol. 2012 Oct 15;362(1-2):76-84.
Fujimori C, Ogiwara K, Hagiwara A, Rajapakse S, Kimura A, Takahashi T. Expression of cyclooxygenase-2 and prostaglandin receptor EP4b mRNA in the ovary of the medaka fish, Oryzias latipes: possible involvement in ovulation. Mol Cell Endocrinol. 2011 Jan 30;332(1-2):67-77.
Academic degreePh. D.
Academic background2008 B.S., Hokkaido University
2013 Ph. D., Hokkaido University
2013-2016 Postdoctoral researcher, National Institute for Basic Biology
2016-2017 Postdoctoral researcher, Nagoya University
2017-2022 Postdoctoral researcher, The University of Tokyo
2022-2023 Postdoctoral researcher, National Institute for Basic Biology
2023- Assistant Professor, Hokkaido University
Room addressScience Building 5 5-1006

Department of Biological Sciences, Reproductive and Developmental Biology

Fujimori Chika

Assistant Professor

What is your dream that you want to achieve through your research?

I am now studying the evolution of hormones related to reproduction, and I would like to share the excitement of new discoveries with the colleagues I work with. I also want to share the worries and joys of conducting experiments, examining hypotheses, and challenges that need to be overcome.

What made you decide to become a researcher?

I have always loved animals, and I was fascinated by the principles of biology and the process of elucidating them that my high school teachers talked about, and I entered Hokkaido University because I wanted to see what research activities were like. Research includes more simple tasks than I had previously imagined, and there are many unexpected difficulties. But the process of accumulating results to reveal the unknown is very fascinating.

Free subject

The phrase from senior professor “Research is all about relationship,” was very impressive to me. In the rapidly advancing field of biological science, it is difficult to accomplish research alone (in fact, nowadays single-authored research papers are rarely seen). Therefore, collaborating with other researchers, including lab members, is essential to progress in research. Communicating with and developing trust relationship with many researchers is believed to be the key to advancing research and realizing the dream of sharing the excitement I mentioned above.

Photo with lab members(I am the second from the front)