Researcher Information

Hideaki Oikawa

Specially Appointed Professor

Department of Chemistry, Organic and Biological Chemistry

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Representative Achievements

Efficient reconstitution of Basidiomycota diterpene erinacine gene cluster in Ascomycota host Aspergillus oryzae based on genomic DNA sequences.
Liu, C.; Minami, A.; Ozaki, T.; Wu, J.; Kawagishi, H.; Maruyama, J.; Oikawa, H.; J. Am. Chem. Soc. 2019, 141, 15519-15523
Unveiling the Biosynthetic Pathway of the Ribosomally Synthesized and Post-translationally Modified Peptide Ustiloxin B in Filamentous Fungi.
Ye, Y.; Minami, A.; Igarashi, Y.; Izumikawa, M.; Umemura, M.; Nagano, N.; Machida, M.; Kawahara, T.; Shin-ya, K.; Gomi, K.; Oikawa, H.; Angew. Chem. Int. Ed. 2016, 55, 8072-8075
Reconstitution of biosynthetic machinery for highly elaborated indole diterpene penitrem.
Liu, C. W.; Tagami, K.; Minami, A.; Matsumoto, T.; Frisvad, J. C.; Suzuki, H.; Ishikawa,J.; Gomi, K.; and Oikawa, H. Angew. Chem. Int. Ed. 2015, 54, 5748-5752
Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.
Hotta, K.; Chen, X.; Paton, R. S.; Minami, A.; Li, H.; Swaminathan, K.; Mathews, I. I.; Watanabe, K.; Oikawa, H.; Houk, K. N.; Kim, C. -Y. Nature 2012, 483, 355-358
Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.
Koketsu, K.; Watanabe, K.; Suda, H.; Oguri, H.; Oikawa, H. Nat. Chem. Biol., 2010, 6, 408-410.
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Academic degreePh. D.
Academic background1979 B. Sc., Hokkaido University, Sapporo, Japan
1981 MS, Hokkaido University
1984 Ph. D. (Agriculture), Hokkaido University
1984〜1985 Postdoctoral fellow, Brown University
1985〜1986 Postdoctoral fellow, RIKEN
1986〜1998 Instructor, Faculty of Agriculture, Hokkaido University
1999〜2002 Associate Professor, Faculty of Agriculture, Hokkaido University
2003〜Present Professor, Faculty of Science, Hokkaido University
Affiliated academic societyThe Chemical Society of Japan, American Chemical Society, The Japan Society for Bioscience, Biotechnology, and Agrochemistry
Room addressScience Building 7 7-409