
Representative Achievements
Unveiling biosynthesis of the phytohormone abscisic acid in fungi: Unprecedented mechanism of core scaffold formation catalyzed by an unusual sesquiterpene synthase, Takino, J.; Kozaki, T.; Sato, Y.; Liu, C.; Ozaki, T.; Minami, A.; Oikawa, H. J. Am. Chem. Soc. 2018, 140, 12392-12395.
Total biosynthesis of antiangiogenic agent (-)-terpestacin by artificial reconstitution of the biosynthetic machinery in Aspergillus oryzae, Narita, K.; Minami, A.; Ozaki, T.; Liu, C.; Kodama, M.; Oikawa, H. J. Org. Chem., 2018, 83, 7042-7048.
Focused genome mining of structurally related sesterterpenes: enzymatic formation of enantiomeric and diastereomeric products, Narita, K.; Sato, H.; Minami, A.; Kudo, K.; Gao, L.; Liu, C.; Ozaki, T.; Kodama, M.; Lei, X.; Taniguchi, T.; Monde, K.; Yamazaki, M.; Uchiyama, M.; Oikawa, H. Org. Lett., 2017, 19, 6696-6699.
Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis, Ugai, T.; Minami, A.; Fujii, R.; Tanaka, M.; Gomi, K.; Oikawa, H. Chem. Commun., 2015, 51, 1878-1881.
Sequential enzymatic epoxidation involved in polyether lasalocid biosynthesis, Minami, A.; Shimaya, M.; Suzuki, G.; Migita, A.; Shinde, S. S.; Sato, K.; Watanabe, K.; Tamura, T.; Oguri, H.; Oikawa, H. J. Am. Chem. Soc., 2012, 134, 7246-7249.

Related industries
Pharmaceuticals, Agricultural Chemistry
Academic degree | Ph.D. |
Academic background | BS. Science, School of Science, Tokyo Institute of Technology: Mar, 2002. MS. Science, Graduate School of Science, Tokyo Institute of Technology: Mar, 2004. PhD. Science, Graduate School of Science, Tokyo Institute of Technology: Mar, 2007. Postdoctoral Fellow at Biotechnology Research Center, Toyama Prefectural University: April, 2007-May, 2008 Assistant Professor at Graduate School of Science, Hokkaido University: April, 2008-June, 2015 Associate Professor at Graduate School of Science, Hokkaido University: July, 2015-present |
Affiliated academic society | The Chemical Society of Japan, Japan Society for Bioscience, Biotechnology, and Agrochemistry |
Project | Grant-in-Aid for Scientific Research on Innovative Areas 「Creation of Complex Functional Molecules by Rational Redesign of Biosynthetic Machineries」 |
Room address | General Research Building 7 04-07 |